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Clareo Health | Breast Cancer Clinical Trials in Pittsburgh | 472 Studies

Clinical Trials Breast CancerPittsburgh

Breast Cancer Clinical Trials in Pittsburgh

Find 472 clinical trials for breast cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Pittsburgh

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 261-280 of 472 trials

CompletedA Study of Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Operable HER2-Positive Primary Breast CancerThis two-arm, randomized, open-label, multicenter study will evaluate the efficacy and safety of trastuzumab emtansine in combination with pertuzumab versus trastuzumab in…NCT01966471·Scottsdale, Arizona and 294 others

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Data from ClinicalTrials.govTerms

CompletedEXERT-BCN: an Exercise and Nutrition Regimen to Designed to Improve Body Composition After Treatment for Breast CancerThis protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound…NCT05978960·Pittsburgh, Pennsylvania

CompletedLymph Node Removal in Treating Women Who Have Stage I or Stage IIA Breast CancerRATIONALE: Surgery to remove lymph nodes in the armpit may remove cancer cells that have spread from tumors in the breast.NCT00003855·Birmingham, Alabama and 155 others

CompletedFulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-PositiveThis randomized phase III trial studies fulvestrant and lapatinib to see how well they work compared to fulvestrant and a placebo in treating postmenopausal women with stage III…NCT00390455·Little Rock, Arkansas and 367 others

CompletedA Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast CancerThe purpose of this study was to evaluate the efficacy of enzalutamide with trastuzumab in patients with HER2+ AR+ metastatic or locally advanced breast cancer.NCT02091960·Anaheim, California and 38 others

UnknownLetrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast CancerRATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes.NCT00382070·Anniston, Alabama and 805 others

RecruitingA Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer PatientsThe purpose of this research is to learn if the CellSearch Circulating Tumor Cells (CTC) test can help doctors in making decisions about treatment and monitoring of breast cancer.NCT06833853·Pittsburgh, Pennsylvania

CompletedCombination of Weekly Paclitaxel With Neratinib and Trastuzumab in Women With Metastatic HER2-positive Breast CancerThe FB-8 study is designed as an open label, single arm, Phase I dose-escalation study evaluating the combination of weekly paclitaxel with neratinib and trastuzumab in women with…NCT01423123·New Brunswick, New Jersey and 3 others

CompletedINCB106385 Alone or in Combination With Immunotherapy in Advanced Solid TumorsThis is a multicenter, open-label, dose-escalation/dose-expansion Phase 1 clinical study to investigate the safety, tolerability, PK profile, pharmacodynamics, and preliminary…NCT04580485·West Hollywood, California and 26 others

RecruitingEvaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25This Phase III Trial will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in…NCT05879926·Birmingham, Alabama and 1260 others

CompletedMeasuring Patient Satisfaction and Quality of Life Following Body Image Altering SurgeryThe goal of this study is to develop a questionnaire to measure patient satisfaction with their breast surgery.NCT00605670·Baltimore, Maryland and 4 others

CompletedA Trial of Paclitaxel and Bevacizumab vs. Gemcitabine, Paclitaxel, and Bevacizumab in Advanced Breast CancerThis study will compare the cancer response to both treatments for locally advanced or metastatic breast cancerNCT00320541·Fayetteville, Arkansas and 31 others

CompletedScreening Contrast-Enhanced Mammography as an Alternative to MRIThere are women for whom a screening breast MRI is clinically recommended, but not feasible either due to patient factors (body habitus, pacemaker or other implant…NCT04764292·Cranberry Township, Pennsylvania and 2 others

CompletedType I-Polarized Autologous Dendritic Cell Vaccine With Tumor Blood Vessel Antigen-Derived Peptides in Metastatic Breast Cancer PatientsThis pilot clinical trial studies the safety of a dendritic cell vaccine when given with gemcitabine hydrochloride in treating patients with breast cancer that has spread beyond…NCT02479230·Cleveland, Ohio and 1 other

CompletedEvaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)The purpose of this study is to compare the safety and efficacy of nab-paclitaxel in combination with either gemcitabine or carboplatin to the combination of gemcitabine and…NCT01881230·Chandler, Arizona and 139 others

TerminatedEvaluation of Mammographic Breast Density in Participants with Hormone Receptor-Negative Breast Cancer Enrolled on Study A011502This phase III trial evaluates mammographic breast density in participants with hormone receptor-negative breast cancer enrolled on study A011502.NCT03609021·Fairbanks, Alaska and 514 others

RecruitingQuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast CancerThis study will assess whether a quantitative, HER2 assay can accurately and reliably discriminate between responders and non-responders among patients with HER2 IHCI+ metastatic…NCT06551116·San Francisco, California and 36 others

RecruitingEXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)The EXActDNA-003 study will prospectively enroll participants who are planning to undergo chemotherapy for high-risk, early breast cancer, who are willing to provide tissue and…NCT06401421·Anchorage, Alaska and 57 others

TerminatedHER-Seq: A Blood-based Screening Study to Identify Patients With HER2 Mutations for Enrollment Into Clinical Research Studies of NeratinibThis is a multi-center, observational genomic screening protocol to identify participants whose tumors harbor somatic mutations in the ERBB2 (HER2) gene, as measured in…NCT03786107·Pittsburgh, Pennsylvania and 21 others

CompletedA Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast CancerThe purpose of this study is to evaluate the safety, efficacy, and pharmacokinetics of tiragolumab in combination with atezolizumab and chemotherapy in participants with…NCT04584112·Birmingham, Alabama and 23 others

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