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Clareo Health | Breast Cancer Clinical Trials in Pittsburgh | 476 Studies

Clinical Trials Breast CancerPittsburgh

Breast Cancer Clinical Trials in Pittsburgh

Find 476 clinical trials for breast cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 476 trials

CompletedA Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast CancerThis study is being done for the following reasons: * The study has two parts.NCT02236000·Weston, Florida and 14 others CompletedVeliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid CancerThis phase I trial is studying the side effects and best dose of veliparib when given together with carboplatin and paclitaxel in treating patients with advanced solid cancer.NCT00535119·Duarte, California and 6 others

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Data from ClinicalTrials.govTerms

TerminatedEfficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast CancerSTAGE 1: To determine the safety of enobosarm 9 milligram (mg) once daily (QD) used in combination with a CDK 4/6 inhibitor \[Verzenio® (abemaciclib) tablets, for oral use, 150 mg…NCT05065411·Chandler, Arizona and 29 others

CompletedEarly Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast CancerRATIONALE: The primary tumor might be a source of re-seeding of distant sites and therefore elimination of this source of metastasizing cells by early local therapy may be of…NCT01242800·Mobile, Alabama and 376 others

Active not recruitingVeliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney DysfunctionThis phase I trial studies the side effects and the best dose of veliparib when given together with paclitaxel and carboplatin in treating patients with solid tumors that are…NCT01366144·Duarte, California and 16 others

RecruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening TrialThis ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing.NCT05564377·Birmingham, Alabama and 483 others

CompletedDelphinus SoftVue Prospective Case Collection - ARM 1The SoftVue™ is a whole breast ultrasound system with an automated scanning curvilinear ring-array transducer that employs UST.NCT03257839·Los Angeles, California and 9 others

CompletedThe Effect of Aromatase Inhibitors on Cardiovascular Risk Factors in Women With Breast CancerThis study explores how aromatase inhibitor therapy affects risk factors for heart disease in postmenopausal women with breast cancer.NCT01080170·Pittsburgh, Pennsylvania

CompletedA Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast CancerThis randomized, double-blind, placebo-controlled, two-arm study will assess the safety and efficacy of pertuzumab in addition to chemotherapy plus trastuzumab as adjuvant therapy…NCT01358877·Scottsdale, Arizona and 545 others

CompletedEXERT-BCN: an Exercise and Nutrition Regimen to Designed to Improve Body Composition After Treatment for Breast CancerThis protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound…NCT05978960·Pittsburgh, Pennsylvania

CompletedPharmacokinetics And Pharmacodynamics Of Lapatinib In Two Dosing Regimens In Treatment-naive Patients With Breast CancerThis study will examine the inhibition of ErbB1 and ErbB2 phosphorylation and downstream mediators of tumor cell growth and survival tumor tissue in treatment-naive breast cancer…NCT00359190·Miami, Florida and 9 others

Active not recruitingExemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or MetastaticThis randomized phase III trial studies exemestane and entinostat to see how well they work compared to exemestane alone in treating patients with hormone receptor-positive breast…NCT02115282·Birmingham, Alabama and 652 others

CompletedSPI-2012 vs Pegfilgrastim in the Management of Neutropenia in Participants With Breast Cancer With Docetaxel and Cyclophosphamide (ADVANCE)The purpose of this study was to compare the efficacy of a single dose of SPI-2012 versus pegfilgrastim in participants with early-stage breast cancer receiving docetaxel and…NCT02643420·Glendale, Arizona and 80 others

RecruitingA Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or…NCT06022029·Los Angeles, California and 15 others

Active not recruitingDigital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast CancerThis randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer.NCT03233191·Birmingham, Alabama and 148 others

TerminatedA Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsThis study will evaluate the efficacy and safety of alectinib in participants with Anaplastic Lymphoma Kinase (ALK)-positive locally advanced or metastatic solid tumors other than…NCT04644315·Culver City, California and 28 others

CompletedOral Drug Study In Women With Refractory Metastatic Breast Cancer After First-line or Second-line Herceptin.The purpose of this study is to determine the efficacy of an oral investigational drug for the treatment of metastatic breast cancer tumors that are known to overexpress HER2/neu.NCT00051103·Chula Vista, California and 29 others

CompletedDocetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast CancerRATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of breast cancer cells, either by killing the cells or by stopping them from dividing.NCT01547741·Anchorage, Alaska and 914 others

RecruitingA Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)The purpose of this study is to understand treatment adherence and patient-reported outcomes of switching to giredestrant due to prior aromatase inhibitor (AI) intolerance.NCT07541079·Huntsville, Alabama and 12 others

CompletedNBRST: Prospective Neo-adjuvant REGISTRY TrialThe scope of this registry study is to measure chemosensitivity as defined by pCR (primary endpoint), or endocrine sensitivity as defined by partial response (decrease in longest…NCT01479101·Glendale, Arizona and 75 others

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