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Clareo Health | Breast Cancer Clinical Trials in Massachusetts | 1,146 Studies

Clinical Trials Breast CancerMassachusetts

Breast Cancer Clinical Trials in Massachusetts

Find 1,146 clinical trials for breast cancer near Massachusetts. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 1,146 trials

UnknownSafety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast CancerThis study is a Phase 1 and pharmacologic open-label dose-escalation trial using a "3+3" design.NCT01304797·San Francisco, California and 4 others Active not recruitingS0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast CancerRATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die.NCT00070564·Anniston, Alabama and 541 others

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Data from ClinicalTrials.govTerms

CompletedARRY-380 + Trastuzuamab for Breast w/ Brain MetsThe purpose of this study is to test the safety of different doses of ARRY-380 in combination with trastuzumab.NCT01921335·Boston, Massachusetts and 1 other

CompletedBevacizumab in Combination With Vinorelbine and Trastuzumab for HER2-Positive, Metastatic Breast CancerThe purpose of this research study is to determine the effects of the combination of bevacizumab, vinorelbine, and trastuzumab on participants and their cancer.NCT00670982·Hartford, Connecticut and 6 others

RecruitingA Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid TumorsThis is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2.NCT05150691·Cerritos, California and 101 others

RecruitingRibociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast CancerThis is an open label, multicenter, single arm phase II study to evaluate the efficacy and safety of ribociclib and ET in patients with locoregional recurrence of HR-positive…NCT05467891·Birmingham, Alabama and 20 others

Active not recruitingNeoadjuvant Her2-targeted Therapy and Immunotherapy With Pembrolizumab [IIT2018-04-MCARTHUR-NEOHP]A phase 2 open-label, randomized, multi-center trial to evaluate the efficacy and safety of neoadjuvant trastuzumab, pertuzumab and weekly paclitaxel (THP) as compared to…NCT03747120·Los Angeles, California and 4 others

TerminatedGDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastatic Breast CancerThis phase I/II trial study evaluates the tolerability and best tolerated dose of the PI3K inhibitor GDC-0941 when given with the chemotherapy cisplatin.NCT01918306·Birmingham, Alabama and 15 others

CompletedStudy of Efficacy and Safety of LEE011 in Postmenopausal Women With Advanced Breast CancerThe primary purpose of this study was to assess the efficacy of ribociclib, as measured by progression free survival (PFS), in postmenopausal women with hormone receptor positive…NCT01958021·Chandler, Arizona and 220 others

Active not recruitingA Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)This research study is being done to evaluate the safety and effectiveness of sacituzumab govitecan with trastuzumab (Herceptin, Herceptin Hylecta, or trastuzumab biosimilar) in…NCT06100874·Miami, Florida and 3 others

RecruitingA Study of LY4175408 in Participants With Advanced CancerThe purpose of this study is to measure the safety and efficacy of LY4175408 in participants with selected advanced cancer.NCT07046923·Stanford, California and 26 others

TerminatedPhase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast CancerThis study is a multi-center, randomized, double-blind, placebo-controlled, Phase 2 study in postmenopausal women with heregulin positive, hormone receptor positive, HER2 negative…NCT03241810·Chandler, Arizona and 58 others

RecruitingPhase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or without obinutuzumab…NCT04787042·Scottsdale, Arizona and 5 others

CompletedPaclitaxel With / Without GW572016 (Lapatinib) As First Line Therapy For Women With Advanced Or Metastatic Breast CancerThe purpose of this study is to determine the efficacy and safety of an oral dual tyrosine kinase inhibitor (GW572016) in combination with paclitaxel compared to paclitaxel alone…NCT00075270·Tucson, Arizona and 176 others

Active not recruitingSafety and Tolerability of IPH4502 in Patients With Advanced Solid TumorsThis is a first-in-human, open-label, multicenter, Phase 1 study to evaluate the safety, tolerability and preliminary efficacy of IPH4502 and to determine the recommended Phase 2…NCT06781983·Boston, Massachusetts and 6 others

RecruitingStudy of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid MalignanciesThis study will assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AZD9574 individually and in combination with anti-cancer…NCT05417594·La Jolla, California and 31 others

CompletedLapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain MetastasesLapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for their growth.NCT00098605·Boston, Massachusetts

RecruitingThe Cancer of the Pancreas Screening-5 CAPS5)StudyJohns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins.NCT02000089·New Haven, Connecticut and 8 others

CompletedA Phase 1/2 Safety Study of Intratumorally Dosed INT230-6This study evaluated the intratumoral administration of escalating doses of a novel, experimental drug, INT230-6.NCT03058289·Los Angeles, California and 7 others

CompletedUpstaging of ALH/LCIS Found on Core Biopsy Based on Subsequent Excisional BiopsyThe goal of this study is to determine how often patients who have atypical lobular hyperplasia (ALH) or lobular carcinoma in situ (LCIS) on core needle biopsy of an imaging…NCT00146536·Boston, Massachusetts and 1 other

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Other Conditions in Massachusetts

Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma