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Find 799 clinical trials for breast cancer near Maryland. Connect with research centers in your area.
Showing 621-640 of 799 trials
NCT02625935
This multicenter, prospectively designed study examines whether the Prosigna score influences physician and patient adjuvant treatment selection over and above currently used prognostic factors. This study also examines the impact of the test results on patients' reported outcomes, including their decisional conflict status and anxiety levels.
NCT00304941
This study will characterize risk factors associated with breast cancer development in some patients. In particular, it will examine the role of insulin in breast cancer in patients with and without a family history of the disease. Women 30 to 70 years old who have been diagnosed with breast cancer and matched control healthy subjects with and without a family history of breast cancer may be eligible for this study. Participants undergo the following procedures: * Cancer-genetic counseling session, including family history, risk assessment, genetic testing for BRCA1 and BRCA2 (if criteria is met), interpretation of results and management options * Medical history, including questions about symptoms or diseases, reproductive history, use of oral contraceptives, body weight, exercise, lifestyle, and demographic issues * Drawing of family tree * Examination of medical records * Blood drawing for genetic and other tests * CT scan of the abdomen (approximate time \< 1 minute) * Filling out questionnaires
NCT00923377
Background: * Research suggests that breast cancers may arise from a population of stem cells in the normal mammary gland that produce clones of cancer cells. * Researchers are now trying to determine what events may initiate the formation of cancer cells. Objectives: * To look for and describe breast stem cells from normal breast tissue from women who do not have breast cancer. * To compare the breast stem cells between women at increased risk for breast cancer and women at average risk for breast cancer. * To show a relationship between the number and type of breast stem cells with the density (appearance) of the mammogram (breast x-ray). * To make cell cultures (grow cells under controlled conditions) from the breast stem cells. Eligibility: -Women 18 years of age and older who are at average or increased risk for breast cancer. Design: Participants complete a health history questionnaire, family history questionnaire and risk assessment questionnaire. * Participants have a mammogram and breast biopsy (surgical removal of a sample of breast tissue). * Women who can become pregnant have a urine pregnancy test....