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Clareo Health | Breast Cancer Clinical Trials in Detroit | 434 Studies

Clinical Trials Breast CancerDetroit

Breast Cancer Clinical Trials in Detroit

Find 434 clinical trials for breast cancer near Detroit, Michigan. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Detroit

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 101-120 of 434 trials

Active not recruitingA Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of giredestrant compared with fulvestrant, both in combination with the…NCT06065748·Daphne, Alabama and 310 others

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Data from ClinicalTrials.govTerms

RecruitingOpen-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced CancerIncyclix Bio (Incyclix) is developing INX-315 as an oral, small molecule inhibitor of cyclin dependent kinase 2 (CDK2) for the treatment of human cancers.NCT05735080·Orlando, Florida and 17 others

RecruitingS1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac ToxicityThis trial has two cohorts of patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body.NCT03418961·Anchorage, Alaska and 589 others

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

CompletedAprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell TransplantRATIONALE: Antiemetic drugs, such as aprepitant, granisetron, and dexamethasone, may help lessen or prevent nausea and vomiting in patients treated with chemotherapy.NCT00293384·Detroit, Michigan

TerminatedGEN1047 for Solid Tumors - First in Human (FIH) TrialThe purpose of this trial is to measure the following in participants with solid tumors who receive GEN1047: * The side effects seen with GEN1047 * What the body does with…NCT05180474·Los Angeles, California and 35 others

TerminatedStudy of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)The purpose of this study is to compare the efficacy of olaparib (MK-7339) plus pembrolizumab (MK-3475) with chemotherapy plus pembrolizumab after induction with first-line…NCT04191135·Monterey, California and 121 others

CompletedA Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast CancerThis study is looking at whether Metformin, an agent that is commonly used to treat diabetes, can decrease or affect the ability of breast cancer cells to grow and whether…NCT01101438·Anchorage, Alaska and 343 others

TerminatedA Study of NM21-1480 in Adult Patients With Advanced Solid TumorsThis is a first-in-human, open-label, multi-center, Phase 1/2, dose-escalation study with expansion cohorts to evaluate NM21-1480 for safety and immunogenicity, to determine the…NCT04442126·Fort Collins, Colorado and 25 others

Active not recruitingUsing FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE StudyThis phase II trial studies how well FDG-PET/CT works in assessing the response of patients with breast cancer that has spread to the bones or mostly to the bones (bone-dominant…NCT04316117·Birmingham, Alabama and 103 others

UnknownStudy of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 SignalingThis is a prospective, single arm, open label, multicenter interventional study designed to evaluate the efficacy of neoadjuvant chemotherapy with anti-HER2 antibodies in patients…NCT03412643·Colton, California and 42 others

CompletedDS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]This study will compare DS 8201a to standard treatment. Participants must have HER2 breast cancer that has been treated before.NCT03523585·Chandler, Arizona and 226 others

Active not recruitingRobotic vs. Open NSM for Early Stage Breast CancerThis study evaluates the safety and effectiveness of the da Vinci SP Surgical System compared to Open NSM in Nipple Sparing Mastectomy procedures.NCT05720039·Irvine, California and 14 others

TerminatedRO4929097 and Vismodegib in Treating Patients With Breast Cancer That is Metastatic or Cannot Be Removed By SurgeryThis phase I trial studies the side effects and best dose of RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) when given together with vismodegib in…NCT01071564·Baltimore, Maryland and 2 others

CompletedA Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid TumorsAn open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination…NCT03595059·Birmingham, Alabama and 39 others

Active not recruitingCapivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBCPhase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer…NCT03997123·Whittier, California and 259 others

Active not recruitingVeliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney DysfunctionThis phase I trial studies the side effects and the best dose of veliparib when given together with paclitaxel and carboplatin in treating patients with solid tumors that are…NCT01366144·Duarte, California and 16 others

CompletedStudy of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast CancerThe objective of this study is to assess efficacy and safety of radium 223 dichloride in subjects with human epidermal growth factor receptor 2 (HER2) negative hormone receptor…NCT02258451·La Jolla, California and 91 others

CompletedCognition in the Study of Tamoxifen and RaloxifeneThe purpose of this study is to assess the effects of tamoxifen and raloxifene on cognitive aging in selected cognitively-healthy women.NCT00687102·Phoenix, Arizona and 133 others

CompletedBiological Therapy in Treating Women With Stage IV Breast CancerRATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing.NCT00027807·Detroit, Michigan

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