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Clareo Health | Brain Cancer Clinical Trials in Massachusetts | 161 Studies

Clinical Trials Brain CancerMassachusetts

Brain Cancer Clinical Trials in Massachusetts

Find 161 clinical trials for brain cancer near Massachusetts. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 161 trials

CompletedCOL-3 in Treating Patients With Progressive or Recurrent Brain TumorsRATIONALE: COL-3 may stop the growth of brain tumors by stopping blood flow to the tumor.NCT00004147·Birmingham, Alabama and 8 others CompletedImmunotoxin Therapy in Treating Patients With Malignant GliomaRATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. This may be an effective treatment for malignant glioma.NCT00006268·Birmingham, Alabama and 10 others

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Data from ClinicalTrials.govTerms

TerminatedTP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade GliomaRATIONALE: The TP-38 toxin can locate tumor cells and kill them without harming normal cells. Giving TP-38 toxin directly into the tumor may kill more tumor cells.NCT00074334·Washington D.C., District of Columbia and 7 others

CompletedBIBF 1120 for Recurrent High-Grade GliomasBIBF 1120 is a newly discovered compound that may stop cancer cells from growing abnormally.NCT01380782·Boston, Massachusetts and 3 others

RecruitingStudy of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantThe goal of this study is to determine the efficacy of the 1) ribociclib and everolimus to treat pediatric and young adult patients newly diagnosed with a high-grade glioma (HGG)…NCT05843253·Aurora, Colorado and 19 others

RecruitingImplantable Microdevice In Primary Brain TumorsThis pilot study will assess the safety and feasibility of using an implantable microdevice to measure local intratumor response to chemotherapy and other clinically relevant…NCT04135807·Boston, Massachusetts

CompletedCilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor)This study will investigate clinical activity, safety, and tolerability of the anti-angiogenic compound cilengitide (EMD 121974) in the treatment of first recurrence of…NCT00093964·Birmingham, Alabama and 16 others

TerminatedStudy Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent GliomasThis is an open-label, multicenter, Phase 2 study to evaluate the efficacy and safety of oral selinexor in participants with recurrent gliomas.NCT01986348·Boston, Massachusetts and 5 others

CompletedA Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or ImmunotherapyThis research study is studying the changes in primary and metastatic brain tumor inflammation using positron emission tomography (PET) imaging using a radioactive substance…NCT02431572·Boston, Massachusetts and 1 other

TerminatedStudy to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM SubjectsThe purpose of this study is to assess the safety and tolerability of VBI-1901 in subjects with recurrent malignant gliomas (glioblastoma, or GBM).NCT03382977·Irvine, California and 11 others

CompletedMonitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRIThis research study aims to predict treatment response to anti-angiogenic therapy (Avastin) using advanced magnetic resonance imaging (MRI) and spectroscopy (MRS) for Glioblastoma…NCT02843230·Boston, Massachusetts

CompletedA Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain TumorsThis study will evaluate the administration of AdV-tk followed by valacyclovir in children with malignant glioma, including glioblastoma multiforme (GBM) and anaplastic…NCT00634231·Chicago, Illinois and 1 other

RecruitingThe RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)There are no guidelines or prospective studies defining the optimal surgical treatment for gliomas of older patients (≥70 years) or those with limited functioning performance at…NCT06146725·San Francisco, California and 7 others

CompletedAdavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine GliomasThis phase I trial studies the side effects and the best dose of adavosertib when given together with local radiation therapy in treating children with newly diagnosed diffuse…NCT01922076·Birmingham, Alabama and 23 others

CompletedTemozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00047294·Boston, Massachusetts and 3 others

CompletedPersonalized Translational Platform for Biomarker Discovery in Brain TumorsThe central hypothesis for this proposal is that multimodal (clinical, imaging, tissue) biomarkers will better predict early brain tumor response to treatments and will be more…NCT01240161·San Diego, California and 1 other

CompletedTandutinib in Treating Patients With Recurrent or Progressive GlioblastomaThis phase I/II trial is studying the side effects and best dose of tandutinib and to see how well it works in treating patients with recurrent or progressive…NCT00379080·Birmingham, Alabama and 8 others

CompletedCombination Chemotherapy Plus Gene Therapy in Treating Patients With CNS TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00005796·Indianapolis, Indiana and 1 other

CompletedChemotherapy in Treating Patients With Progressive or Recurrent Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012038·Birmingham, Alabama and 9 others

Active not recruitingPediatric Long-Term Follow-up and Rollover StudyA roll-over study to assess long-term effect in pediatric patients treated with dabrafenib and/or trametinib.NCT03975829·Phoenix, Arizona and 53 others

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Other Conditions in Massachusetts

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia