Brain Cancer Clinical Trials in Houston

Showing 41-60 of 90 trials

Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer

NCT02592356

The goal of this clinical research study is to learn about possible weight, muscle, and/or fat loss in patients receiving cabozantinib or lenvatinib.

Differentiated Thyroid Gland CarcinomaMalignant Adrenal Gland PheochromocytomaMalignant Paraganglioma+1 more

M.D. Anderson Cancer Center23 participantsStarted Nov 2015

Houston, Texas, United States

COMPLETEDPHASE2< 1 mile

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

NCT00704288

The purpose of this study is to evaluate the objective response rate and 6-month progression-free survival rate of XL184 in subjects with recurrent or progressive glioblastoma multiforme. XL184 is a new chemical entity that inhibits VEGFR2, MET and RET, kinases implicated in tumor formation, growth and migration.

Glioblastoma Multiforme

Exelixis222 participantsStarted May 2008

Los Angeles, California, United States • San Francisco, California, United States • Boston, Massachusetts, United States +5 more locations

COMPLETEDPHASE1< 1 mile

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

NCT01922076

This phase I trial studies the side effects and the best dose of adavosertib when given together with local radiation therapy in treating children with newly diagnosed diffuse intrinsic pontine gliomas. Adavosertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Giving adavosertib with local radiation therapy may work better than local radiation therapy alone in treating diffuse intrinsic pontine gliomas.

Anaplastic AstrocytomaAnaplastic OligoastrocytomaDiffuse Intrinsic Pontine Glioma+3 more

National Cancer Institute (NCI)46 participantsStarted Sep 2013

Birmingham, Alabama, United States • Los Angeles, California, United States • Orange, California, United States +21 more locations

Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Brain Cancer Trials in Other Cities

Expanded Access Protocol Using 131I-MIBG

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma

UNITE Study: Understanding New Interventions With GBM ThErapy

Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent Glioblastoma

Gliogene: Brain Tumor Linkage Study

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Other Conditions in Houston