Brain Cancer Clinical Trials in Baltimore

Showing 141-160 of 267 trials

Metformin in Children With Relapsed or Refractory Solid Tumors

NCT01528046

The purpose of this study is to evaluate the tolerability and safety of escalating doses of metformin on a backbone of vincristine, irinotecan and temozolomide (VIT) in children with recurrent and refractory solid tumors.

Solid TumorsPrimary Brain Tumors

H. Lee Moffitt Cancer Center and Research Institute26 participantsStarted Sep 2012

Hartford, Connecticut, United States • Wilmington, Delaware, United States • Gainesville, Florida, United States +11 more locations

COMPLETEDPhase 1< 1 mile

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

NCT02311920

This phase I trial studies the safety and best dose of ipilimumab, nivolumab, or both in combination with temozolomide in treating patients with newly diagnosed glioblastoma or gliosarcoma. Monoclonal antibodies, such as ipilimumab and nivolumab, may block tumor growth in different ways by targeting certain cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known which combination is a better treatment for glioblastoma or gliosarcoma.

GliosarcomaSupratentorial Glioblastoma

National Cancer Institute (NCI)32 participantsStarted Apr 2015

San Francisco, California, United States • Atlanta, Georgia, United States • Baltimore, Maryland, United States +8 more locations

Metformin in Children With Relapsed or Refractory Solid Tumors

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Brain Cancer Trials in Other Cities

Incidence of Intracranial Hemorrhage in Glioma Patients With Venous Thromboembolism Converted From LMWH to Apixaban

Phase 2 Study of Durvalumab (MEDI4736) in Patients With Glioblastoma

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme

Ketogenic Diet Treatment Adjunctive to Radiation and Chemotherapy in Glioblastoma Multiforme: a Pilot Study

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

3D Prediction of Patient-Specific Response

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Expanded Access Protocol Using 131I-MIBG

Evaluation of GLR2007 for Advanced Solid Tumors

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma

Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

A Study in Subjects With Recurrent Malignant Glioma

Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM)

Other Conditions in Baltimore