Bipolar Disorder Clinical Trials

Showing 261-280 of 605 trials

Gabapentin for Bipolar & Cannabis Use Disorders

NCT03334721

The proposed 2-week, double-blind, crossover, proof of concept study aims to measure and manipulate core neurochemical (i.e., dysregulated brain GABA/glutamate homeostasis) and neurobehavioral (i.e., elevated impulsivity) dysfunctions characteristic of individuals with cannabis use disorder (CUD) and Bipolar Disorder (BD), using a medication that has been shown to increase cortical GABA (i.e., gabapentin) levels in past research, and to evaluate medication-related changes in response inhibition (go no-go) and cannabis cue reactivity functional Magnetic Resonance Imaging tasks, as well as cannabis use, mood symptoms (including anxiety and sleep), and impulsivity in individuals with CUD+BD.

Bipolar I DisorderBipolar II DisorderCannabis Use Disorder+1 more

Medical University of South Carolina23 participantsStarted Oct 2017

Charleston, South Carolina, United States

COMPLETED

Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder

NCT02655978

The overall goal of this study is to employ diffusion-weighted imaging (DWI) and tractography to investigate differences in connectivity in the rostral dorsal cingulum bundle (CB) in patients with bipolar disorder type I (BDI) or bipolar type II (BDII) compared to matched controls, and to utilize this information to determine if high-frequency deep brain stimulation (DBS) of the rostral dorsal CB has realistic potential as a therapy for producing mood stabilization in patients with BDI or BDII.

Bipolar Disorder

University Hospitals Cleveland Medical Center45 participantsStarted Jan 2016

Cleveland, Ohio, United States

COMPLETEDNA

Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness

NCT03062267

Testing an mHealth mobile interventionist texting program on illness management.

Schizoaffective DisorderSchizophreniaBipolar Disorder+1 more

University of Washington49 participantsStarted Oct 2017

Chicago, Illinois, United States • Spokane, Washington, United States

Gabapentin for Bipolar & Cannabis Use Disorders

Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder

Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness

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Clinical Determinants of the Discrepancy Between Objective and Subjective Cognition in the Versailles FACE-BD Cohort

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