Asthma Clinical Trials

Showing 1761-1780 of 4,312 trials

A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma

NCT05528679

This study will assess the efficacy and safety of 610 as an adjunctive therapy in adult subjects with severe eosinophilic asthma.

Asthma

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.120 participantsStarted Sep 2022

Shanghai, Shanghai Municipality, China

UNKNOWNNA

Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19

NCT05359770

COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e. pain, fatigue), neurological complications and and mainly disorders of the respiratory system, such as respiratory muscle weakness after hospital discharge. Many therapeutic approaches such as transcranial direct current stimulation (tDCS) have been proposed to minimize functional and structural impairments. The aim of the present study is to evaluate the effects of inspiratory muscle training associated with stimulation of the diaphragmatic motor cortex through hd-tdcs in post-COVID-19 patients on inspiratory muscle strength, pulmonary function, inflammatory levels and functional capacity.

CoronavirusInspiratory Muscle TrainingRespiratory Infection+1 more

Suellen Marinho Andrade30 participantsStarted Sep 2021

João Pessoa, Paraíba, Brazil

UNKNOWNNA

High Flow Nasal Cannula Versus Non-Invasive (NIV)in Both Hypoxemic and Hypercapnic Respiratory Failure.

NCT05499039

high flow nasal cannula (HFNC) oxygen therapy utilizes an air oxygen blend allowing from 21 % to 1 00% FiO2 delivery and generates up to 60 L/min flow rates The gas is heated and humidified through an active heated humidifier and delivered via a single limb heated inspiratory circuit (to avoid heat loss and condensation) to the patient through a large diameter nasal cannula Theoretically, HFNC offers significant advantages in oxygenation and ventilation over COT. Constant high flow oxygen delivery provides steady FiO2 and decreases oxygen dilution. It also washes out physiologic dead space and generates positive end expiration pressure (PEEP) that augments ventilation The heated humidification facilitates secretion clearance, decreases bronchospasm, and maintains mucosal integrity. This study aims to evaluate the effectiveness of HFNC compared to NIMV in management of Acute hypoxemic and acute hypercapneic respiratory failure

Acute Hypoxemic Respiratory FailureAcute Hypercapnic Respiratory Failure

Assiut University80 participantsStarted Oct 2022

Asyut, Egypt

A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma

Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19

High Flow Nasal Cannula Versus Non-Invasive (NIV)in Both Hypoxemic and Hypercapnic Respiratory Failure.

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