Asthma Clinical Trials

Showing 1001-1020 of 4,312 trials

Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients

NCT06229886

Prospective observational cohort study within the Pediatric Intensive Care Unit (PICU). We will perform point-of-care-ultrasound (POCUS) to quantify tricuspid regurgitant jet velocity (TRJV) on mechanically ventilated (MV) children. Mechanically ventilated (MV) children approaching extubation as per the discretion of the PICU clinical team will undergo a positive end expiratory pressure (PEEP) titration protocol in a safe and timely manner in the PICU. During this PEEP titration, POCUS will be performed by a pediatric intensivist and interpreted by a pediatric cardiologist. Medical demographics will be collected from the electronic medical record and recorded.

Tricuspid RegurgitationMechanical Ventilation Pressure HighPediatric Respiratory Diseases

Northwell Health20 participantsStarted Dec 2023

New Hyde Park, New York, United States

COMPLETEDNA

Effect of Volume Guarantee-High Frequency Oscillatory Ventilation on Cerebral Blood Flow in Neonates

NCT05592431

A randomized controlled clinical trial evaluates cerebral blood flow changes associated with HFOV-VG in comparison to HFOV alone in preterm neonates with respiratory insufficiency during the period of invasive respiratory support

Infant, Premature, DiseasesRespiratory Tract DiseasesCerebral Blood Flow

Ain Shams University60 participantsStarted Oct 2022

Cairo, Abbasia, Egypt

TERMINATEDPhase 2

A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection

NCT04978337

The purpose of this study is to evaluate the efficacy of rilematovir compared to placebo with respect to the time to resolution of respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD) symptoms.

Respiratory Syncytial Virus

Janssen Research & Development, LLC5 participantsStarted Nov 2021

Birmingham, Alabama, United States • Tempe, Arizona, United States • Bakersfield, California, United States +83 more locations

Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients

Effect of Volume Guarantee-High Frequency Oscillatory Ventilation on Cerebral Blood Flow in Neonates

A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection

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A Safety and Efficacy Study of Mepolizumab in Subjects With Severe Asthma

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PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT

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The ICU LIBERATION Study

Study to Find the Highest Safe Dose of Soluble Guanylate Cyclase (sGC) Activator, BAY 1211163 Administered as Multiple Doses by Inhalation to Patients Who Cannot Breathe by Their Own and Suffer From a Type of Lung Failure That Causes Fluid to Build up in the Lungs Making Breathing Difficult (ARDS)