Asthma Clinical Trials

Showing 601-620 of 2,042 trials

REVErsing Airway Remodelling With Tezepelumab

NCT05651841

The aim of this protocol is to perform a first randomized controlled trial evaluating how Tezepelumab affects the bronchial morphology (and computed tomographic variables in general) of asthmatic patients. In parallel, the investigators also hope to reproduce clinical benefits and perform a transcriptomic study that will juxtapose changes in genetic expression with changes in bronchial morphology and inflammatory signatures. The general hypothesis is that tezepelumab treatment is capable of at least partially reversing bronchial remodelling as detected on computed-tomographic (CT) scans. The investigators also expect such reversal to occur within a unique physiological repair environment that will be reflected by transcriptomic profiles

Airway Remodelling, Asthmatic

University Hospital, Montpellier90 participantsStarted Mar 2023

Dijon, France • Grenoble, France • Le Kremlin-Bicêtre, France +9 more locations

COMPLETEDNA

PNEUMACRIT Device for Neonatal Cardio Respiratory Monitoring

NCT06171867

The usability of a new PNEUMACRIT system is studied in clinical environment in this feasibility study.

Neonatal Respiratory Distress

University of Oulu20 participantsStarted Nov 2023

Oulu, Finland

REVErsing Airway Remodelling With Tezepelumab

PNEUMACRIT Device for Neonatal Cardio Respiratory Monitoring

Related Searches

Ideal Steroids for Asthma Treatment in the PICU

Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery

Single Dose Clinical Trial of MG-ZG122 in Chinese Healthy Adult Subjects

Prototype of Innovative Food Product to Improve Respiratory and Peripheral Muscle Function in Humans

Is Laryngeal Ultrasound Useful in the Assessment for ILO? A Protocol for a Two-stage Exploratory Pilot Study

Early Versus Delayed Intubation of Patients With COVID-19

Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia

Impact of High Flow Therapy on Complications Related to Airway Stenting

Inspiratory Muscle Training in Cerebral Palsy Patients

Study of Diaphragmatic Ultrasound as a Predictor of Mechanical Ventilation in Patients With Respiratory Diseases on Admission to Intensive Care Unit

Impact of Extubation Location After Surgery on Perioperative Times

Project A4sc - An Atlas of Airways at a Single Cell Level

Sorting and Expression Profiling of Airway Cells From Humans (The SEARCH Study)

Effect of an Immune-boosting Food Supplement on the Severity and Frequency of Pediatric Respiratory Tract Infections

Lessening Organ Dysfunction With VITamin C in Septic ARDS

Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

Pragmatic Clinical Trial to Assess the Effectiveness of Pharmaceutical Intervention in Patients With Uncontrolled Asthma

A Clinical Study to Map the HLA Genomic Region in the Greek Population