Asthma Clinical Trials

Showing 521-540 of 3,705 trials

Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction

NCT06953180

This study aims to enhance personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by examining epigenetic factors, predicting biological age and reproductive function using machine learning, and developing health improvement recommendations.

Cardiovascular Diseases (CVD)Type 2 DiabetesChronic Respiratory Diseases+2 more

Asfendiyarov Kazakh National Medical University6,720 participantsStarted Mar 2025

Almaty, Kazakhstan, Kazakhstan

COMPLETEDNA

Adapting Body Reprogramming for Severe Asthma: a Feasibility Study

NCT04980755

There are many symptoms associated with severe asthma, not all of them related to the lung. These are referred to as extra-pulmonary symptoms and their relationship with quality of life is complex. Body reprogramming (BR) is a non-drug intervention originally developed for fibromyalgia patients with the aim of improving health and wellbeing in a personalised way, with evidence-based lifestyle changes. The frequency and severity of multiple symptoms in severe asthma is similar to fibromyalgia and the investigators propose that BR may be a suitable non-drug intervention for severe asthma patients who are about to step up drug treatment. Our study aims are therefore to assess how BR may be suitable for people with severe asthma, and to adapt and optimise the programme for these people. In two phases, severe asthma patients will be recruited via a regional severe asthma clinic at the Royal Devon \& Exeter National Health Service (NHS) Trust and invited to take part in a short course of BR. In phase one, patients will be asked to attend four weekly researcher-led sessions of BR via video call and be given practice tasks to report on at the subsequent session. Questionnaires will be completed for the first and last session. At the end of BR, patients will also be invited to take part in a focus group. The data collected will inform development of the programme for phase two, which will involve recruitment of severe asthma patient who are about to start biologic drug treatment for their severe asthma

Severe Asthma

Royal Devon and Exeter NHS Foundation Trust28 participantsStarted Jul 2021

Exeter, Devon, United Kingdom

Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction

Adapting Body Reprogramming for Severe Asthma: a Feasibility Study

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