Asthma Clinical Trials

Showing 301-320 of 2,042 trials

Bioelectric Impedance in Non-invasive Ventilated Patients: The NIVAR Study.

NCT06996197

Investigators performed a retrospective observational single-centre study in a cohort of COVID-19 patients with AHRF who required NIV support and intensive care unit (ICU) admission from May 2021 to January 2022. A BIA assessment was performed within the first 24 hours after NIV onset. Patient characteristics, severity scores, HACOR score, NIV settings, and mortality were recorded. Cox-hazard multivariate analysis was used to assess the association between BIA parameters and NIV failure, adjusting for potential covariates.

Hypoxemic Acute Respiratory FailureNon Invasive Ventilation (NIV)Bioimpedance Measurement Capacity

Hospital Universitari de Bellvitge74 participantsStarted May 2021

L'Hospitalet de Llobregat, Barcelona, Spain • L'Hospitalet de Llobregat, Barcelona, Spain

RECRUITING

In-depth Analysis of the Immune Responses in the Upper Respiratory Tract in Older Adults Infected or Colonized With Streptococcus Pneumoniae (Spn)

NCT06998251

The NoseSpn-Elderly study aims at characterizing the immune response in the upper respiratory tract in adults aged 60 and over diagnosed with a pneumonia due to a Streptococcus pneumoniae (Spn) infection. The immune response during the acute phase of the infection and after recovery will be compared to the immune response of asymptomatic Spn carriers as well as to the immune response of patients diagnosed with a viral respiratory infection (flu or respiratory syncytial virus (RSV)). The primary objective of this observational study is to quantify the inflammatory response in the nasal cavity and to correlate it with bacterial/viral load and with clinical parameters. The study also aims to compare the inflammatory response measured in the nose to that measured in the blood. Participants will have two study visits including a blood draw, several nasal samplings (nasal lining fluid and nasal cells) and a saliva sampling, one within 72 hours of their hospital admission and another one month later. Nasal lining fluid and saliva will be obtained every two or three days until discharge from the hospital or resolution of symptoms. During those visits, questions regarding symptoms will be asked.

Pneumococcal InfectionsRespiratory Syncytial Virus (RSV) InfectionInfluenza Infection

University Hospital, Geneva280 participantsStarted Dec 2024

Geneva, Switzerland

Bioelectric Impedance in Non-invasive Ventilated Patients: The NIVAR Study.

In-depth Analysis of the Immune Responses in the Upper Respiratory Tract in Older Adults Infected or Colonized With Streptococcus Pneumoniae (Spn)

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