Asthma Clinical Trials

Showing 3061-3080 of 4,312 trials

Relovair PD PK in Chinese Healthy Subjects

NCT01711463

In this study, fluticasone furoate (FF) and vilanterol (VI) in different dose combinations (50/25mcg, 100/25mcg and 200/25mcg) will be administered from a single dry powder device to evaluate the PD, PK, safety and tolerability of the combination in healthy Chinese subjects. The information gathered will be used as a support of the clinical development program of the fixed dose combination of FF/VI inhalation powder in Chinese population.

Asthma

GlaxoSmithKline16 participantsStarted Dec 2012

Beijing, China

COMPLETEDPhase 1

Study to Investigate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of Single & Repeat Doses of GSK2269557

NCT01462617

The study will comprise three Parts: Part A will consist of two cohorts of healthy male volunteers to assess the safety, tolerability and pharmacokinetics of ascending single doses of nebulised GSK2269557. Blinded safety and available PK data will be reviewed before each dose escalation. Part B will be one cohort to examine the safety, tolerability and pharmacokinetics of a repeated dose of GSK2269557 given by nebuliser for 7 days in healthy male volunteers. The total daily dose will be the same as, or lower than, doses that are well tolerated in Part A. Part C will consist of two cohorts of single nebulised doses in healthy male smokers, to assess pharmacodynamic endpoints in sputum and bronchoalveolar lavage.

Asthma

GlaxoSmithKline61 participantsStarted Jul 2011

London, United Kingdom

COMPLETEDNA

Pulmonary Rehabilitation in Asthma Control

NCT03227341

The investigators compared the effectiveness of pulmonary rehabilitation program on asthma control in patients with uncontrolled and partially controlled asthma.

Asthma

Izmir Katip Celebi University45 participantsStarted Jan 2013

Relovair PD PK in Chinese Healthy Subjects

Study to Investigate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of Single & Repeat Doses of GSK2269557

Pulmonary Rehabilitation in Asthma Control

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