Alzheimer's Disease Clinical Trials

Showing 81-100 of 1,974 trials

The Swedish BioFINDER - Preclinical AD Study

NCT06121544

This research study aims to examine biomarkers of Alzheimer's disease (AD) as early as possible which could potentially be a screening tool for the general population. This observational study will take place at the Skåne University Hospital in Sweden. The study will enroll up to 600 cognitively healthy subjects aged 50 to 80 years with 3/4 having preclinical Alzheimer's disease. Recruitment and enrollment will be ongoing for 2-3 years, and subject participation will be lasting approximately 4 years. Disclosure of AD risk assessments will be an optional procedure.

Alzheimer DiseaseMild Cognitive ImpairmentMild Dementia

Skane University Hospital800 participantsStarted Apr 2022

Malmo, Sweden

COMPLETEDPhase 2

A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD

NCT04993755

This is a Phase 2a study to assess the the safety and tolerability of TPN-101 in patients with Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD) Associated with Hexanucleotide Repeat Expansion in the C9orf72 gene (C9ORF72 ALS/FTD).

Amyotrophic Lateral SclerosisFrontotemporal Dementia

Transposon Therapeutics, Inc.42 participantsStarted Oct 2021

La Jolla, California, United States • Orange, California, United States • San Francisco, California, United States +16 more locations

The Swedish BioFINDER - Preclinical AD Study

A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD

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