Alzheimer's Disease Clinical Trials

Showing 221-240 of 1,974 trials

In Vivo PET of Synaptic Density in Cognitive Disorders

NCT05384353

This study will compare the discriminative power of \[18F\]-SynVesT-1 PET and the standard-of-care \[18F\]-FDG PET in different cognitive disorders (Alzheimer's disease, Frontotemporal degeneration, dementia with Lewy bodies and late-life psychiatric disorders). Moreover, changes in \[18F\]-SynVesT-1 PET will be evaluated as well as their correlation with specific symptomatology.

Alzheimer DiseaseFrontotemporal DegenerationDementia With Lewy Bodies+1 more

Universitaire Ziekenhuizen KU Leuven134 participantsStarted Apr 2022

Leuven, Belgium

RECRUITINGPhase 3

[18F]PI-2620 Phase 3 Histopathological Study

NCT05641688

This study is an open-label, multi-center, non-randomized pivotal Phase 3 study to assess the efficacy and safety of PET imaging with \[18F\]PI-2620 for detection of tau deposition in subjects with Alzheimer's disease (AD) and controls during lifetime when compared to histopathology obtained after death and completion of brain autopsy.

Alzheimer Disease

Life Molecular Imaging Ltd200 participantsStarted Dec 2022

Phoenix, Arizona, United States • Sun City, Arizona, United States • Los Angeles, California, United States +22 more locations

In Vivo PET of Synaptic Density in Cognitive Disorders

[18F]PI-2620 Phase 3 Histopathological Study

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