ALS Clinical Trials in New York

Showing 41-60 of 79 trials

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

NCT03626012

The primary objective of this study is to evaluate the safety and tolerability of BIIB078 in adults with C9ORF72-Amyotrophic Lateral Sclerosis (ALS). The secondary objectives of this study are to evaluate the pharmacokinetic profile of BIIB078 and to evaluate the effects of BIIB078 on clinical function. As the first-in-human study, the study enrolls a small number of participants in each cohort. Every participant in a cohort is treated with the same dose or placebo. The study is designed to evaluate and confirm the safety of each dose before enrolling and exposing new participants to a higher dose in the next cohort.

Amyotrophic Lateral Sclerosis

Biogen106 participantsStarted Sep 2018

La Jolla, California, United States • Los Angeles, California, United States • Palo Alto, California, United States +18 more locations

COMPLETED< 1 mile

Deep Phenotyping in Patients With ALS

NCT02819765

This study aims to establish a biorepository and phenotyping database to investigate longitudinal changes in ALS subjects. Blood, including DNA and RNA, cerebrospinal fluid (CSF) and electrophysiologic measures will be collected every 6 months over 1 and a half years. The database and specimen repository will be made available to ALS researchers on a merit basis.

ALSMotor Neuron Disease

Barrow Neurological Institute32 participantsStarted Feb 2017

Phoenix, Arizona, United States • Grand Rapids, Michigan, United States • New York, New York, United States +4 more locations

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A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

Deep Phenotyping in Patients With ALS

ALS Trials in Other Cities

Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)

Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)

Use of Low Cost Prostheses to Improve Upper Extremity Function in Children With Cerebral Palsy

Polysomnography-directed Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)

A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year

BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity

Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

Safety and Efficacy Study of NP001 in Patients With Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation

Virtual Reality and Active Video Games to Improve Balance in Children With Brain Injury

Independent Walking Speed and Crossing a City Street

A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Answer ALS: Individualized Initiative for ALS Discovery

Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)

Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis

Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis

Other Conditions in New York