The study evaluates effects of a single-dose of M640 mg compared to a single dose of tizanidine 8 mg on driving, cognition, sleepiness, and brain activity in healthy adults
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults, aged ≥ 18 and ≤ 65 years of age at the time of consent.
Weigh at least 120 pounds at Screening/Baseline and Baseline.
Medically healthy
Able to take oral medication.
Possesses a valid driver's license.
You may not be if
Current use of any medications known to affect sleep-wake cycle.
Has a sleep disorder.
Positive urine test for amphetamines, barbiturates, cocaine, opiates, benzodiazepines, or cannabinoids
Known history of alcohol or substance use disorder
Participants with a history of cognitive disorders, depression, schizophrenia, panic disorder, or dementia.
Participants with a history of seizure disorder or epilepsy.
Participants with scalp conditions, dermatologic disease, or hair/scalp characteristics
