Comprehensive Information and Analytics Services (CIAS)
Premier, Inc. Applied Sciences
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Aged ≥ 18 years
Had an inpatient encounter to select sites with a cranial or spinal neurological surgery that involves dural sealing performed and discharged during January 1, 2017, and March 31, 2026
Had use of TachoSil® or DuraSeal® sealants during the cranial or spinal neurological surgery as supportive dural sealing method
Note: Any surgery meeting the above criteria is considered index surgery
You may not be if
Index surgery was trauma-related
Had an infection within 7 days prior to index date
Had any neurosurgery involving dural opening during the 12-month look-back period
Had neoplasm of dura mater/meningioma, requiring resection of dura during index visit (the earliest visit meeting selection criteria) or 12-month look-back period
Was pregnant at index visit
Had a CSF leak during the 12-month look-back period
If the surgical approach was transbasal or transpetrosal, if the arachnoid membrane and CSF- containing system remained intact, or if there was \>1 dura opening (excluding extra ventricular or lumbar drains) during index surgery
Had use of Evarrest patch, Tisseel, Adherus, CraniSeal, Duragen, fibrin glue or other dural sealing products during index surgery
Had radiation therapy to surgical field in the 3 months prior to index date
Had chronic corticosteroid use in the 3 months prior to index date
Had both TachoSil® and DuraSeal® used for dural closure during index neurological surgery
