Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
IRCCS San Raffaele Roma
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Individuals diagnosed with relapsing-remitting MS (RRMS);
Age between 18 and 65 years;
EDSS (Expanded Disability Status Scale) score between 0 and 3.5;
No fixed or stable pharmacological therapy;
Three months since the last relapse;
Self-reported persistent fatigue with a significant impact on daily life, assessed using a Visual Analogue Scale (VAS) for fatigue impact, with a score \>20 indicating moderate to severe fatigue;
Ability to understand and sign the informed consent for the study;
Ability to perform the study procedures.
You may not be if
Evidence of clinical relapses and/or steroid treatment (within 6 months prior to study start);
Severe cardiorespiratory disease;
Individuals diagnosed with major depression (DSM-5);
Severe visual impairment;
Severe joint and/or bone disorders interfering with balance and gait (based on clinical judgment);
Recent Botulinum Toxin injection in the affected upper limb, or such an injection planned for the duration of the study;
Interruption of treatment for 1 week or 5 consecutive sessions;
Participation in other interventional studies aimed at fatigue management;
Inability to adhere to the exercise program due to poor compliance;
