This is a phase I study that will investigate \[68Ga\]Ga DOTA-5G in patients with metastatic BC. 10 patients diagnosed with invasive BC will be enrolled.
Age
18–89
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Ability to understand and willingness to sign a written informed consent document.
Men and women age ≥ 18 yrs
Confirmed presence of metastatic breast cancer
Eastern Cooperative Oncology Group Performance Status ≤ 2
Hematologic parameters defined as:
Absolute neutrophil count (ANC) ≥ 1x 109 /L,
Platelet count ≥ 100x 109 /L,
Hemoglobin ≥ 80 g/L.
Blood chemistry levels defined as:
AST, ALT, alkaline phosphatase ≤ 5 times upper limit of normal (ULN),
Total bilirubin ≤ 2 times ULN,
Creatinine ≤ 2 times ULN.
Anticipated life expectancy ≥ 3 months
Able to remain motionless for up to 30-60 minutes per scan.
You may not be if
Pregnant and lactating women
Prisoners
Concurrent malignancy of a different histology that could confound imaging interpretation.
Patients who cannot undergo PET/CT scanning because of weight limits(\>450lbs)
