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Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes

NCT07911007·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Ernesto Maddaloni, MD
CONTACT
+39 0649970952 ernesto.maddaloni@uniroma1.it

Lead

University of Roma La Sapienza

Age

30–any

Sex

ALL

Healthy volunteers

Accepted

You may be eligible if

for people with LADA:
* age at diabetes diagnosis \>30years
* insulin independence for at least 6 months after DM diagnosis and presence of any islet Ab
* diabetes duration \>12 months
* willingness to participate in the study
for participants with T2D:
* diagnosis of T2D made according to the ADA criteria
* diabetes duration \>12 months
* willingness to participate in the study.
for healthy controls:
* age \>30 years
* no previous diagnosis of any form of diabetes
* willingness to participate in the study

You may not be if

cardiac magnetic resonance contraindications
positive history of acute CV disease
cardiomyopathies other than diabetic cardiomyopathy
constrictive pericarditis
cardiac tumor
severe valve disease
active neoplastic disease on ongoing chemotherapy or chest radiotherapy

The record

StatusRecruiting

PhaseNot applicable

Taking part200

StartedJun 2024

UpdatedNov 2, 2026

Conditions

Diabete Mellitus Autoimmune Diabetes Latent Autoimmune Diabetes in Adult (LADA)Type 2 Diabetes Heart Disease+2

Where1

Policlinico Umberto I
Rome, Roma, Italy