Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Assiut University
Age
18–45
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Male sex, aged 18 to 45 years.
Belongs to one of the target diagnostic categories:
* Major Depressive Disorder (currently in clinical remission).
* Bipolar Disorder (in clinical remission/euthymic or manic/hypomanic).
* Healthy control with no personal history of psychiatric or neurological disorders (frequency-matched on age and education).
Smoking exposure status meeting one of the predefined criteria:
* Current active, chronic tobacco cigarette smoker.
* Lifetime never-smoker.
Capable of providing written informed consent and undergoing study assessments.
You may not be if
Pre-existing neurological disorders or psychiatric disorders other than the target mood disorder.
Any current substance use disorder other than tobacco (caffeine use is permitted).
Intellectual disability (IQ \< 70).
Treatment with electroconvulsive therapy (ECT) within the preceding 6 months.
Standard contraindications to magnetic resonance imaging (MRI), including cardiac pacemakers, ferromagnetic or metallic orthopedic implants, severe claustrophobia, or inability to remain still during scanning.
