SURPASS: Stereotactic Ultra-hypofractionated Radiotherapy for Post-prostatectomy Patients: Adaptive Salvage SBRT

Patients will have a computed tomography (CT) or Magnetic resonance imaging (MRI) simulation visit as part of the standard of care (SOC), which will be used for treatment planning. Approximately two weeks after the simulation visit, patients will receive adaptive stereotactic body radiation (SBRT) to the prostate fossa at 35 Gy in 5 fractions on the Unity (MR-linac) or Ethos (CT-linac) as SOC. The radiation treatment used in this study is SOC, however, the doses used are investigational and well supported with evidence from clinical trials.