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Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual Trial

NCT07863180·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Nathan Alexander
CONTACT
734-998-8422 natealex@med.umich.edu
Robert Vangel, BSc
CONTACT
734-936-1168 rvangel@med.umich.edu

Lead

Prabesh Kanel

With

Farmer Family Foundation

This is a sub-study of NCT07154511.

Age

45–any

Sex

ALL

Healthy volunteers

Not accepted

You may be eligible if

Male or Female, age 45 years and over.
Diagnosis of PSP-Richardson syndrome (RS) based on Movement Disorder Society (MDS) Criteria, including
1. Vertical supranuclear gaze palsy.
2. Repeated unprovoked falls OR tendency to fall on the pull test within 3 years.
Access to the internet and webcam for virtual visits.
Presence of a caregiver.

You may not be if

Recent history of significant, uncontrolled GI disease such as Gastroesophageal reflux disease, colorectal cancer.
Significant metabolic or uncontrolled medical comorbidity.
Regular use of typical anti-cholinergic drugs.
Women of child-bearing potential, or who are pregnant and/or nursing.
Suicidal ideation, as indicated by a response of 2 or 3 on question 9 of the Beck Depression Inventory.
Any other condition or criterion that, in the opinion of the investigators, would preclude safe and meaningful participation in the study.

The record

StatusRecruiting

PhasePhase 1–2

Taking part15

StartedOct 2026

UpdatedNov 5, 2026

Conditions

Parkinson Disease Multiple System Atrophy Progressive Supranuclear Palsy(PSP)

Where1

Domino's Farms
Ann Arbor, Michigan, United States