Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mary Phillips, MD MD (Cantab)
With
National Institute on Drug Abuse (NIDA)
Age
18–45
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Between 18-45 years of age
Uses cocaine as a primary drug at a minimum frequency of 1x/mo; any period of abstinence within the past month does not exceed 1 week
You may not be if
Not between 18-45 years of age
Cocaine is not used as a primary drug, is used at a frequency of less than 1x/mo, and/or a period of abstinence lasting longer than 1 week has occurred within past month
Present/lifetime history of primary psychosis or Bipolar Disorder (DSM-5 criteria, SCID-5, SCID-5-PD, YMRS\>10), present suicidal ideation, or current depressive episode
History of head injury, neurological (e.g., epilepsy), pervasive developmental disorder (e.g., autism), systemic medical disease and treatment (medical records, participant report)
Family history of epilepsy
Use of substances with seizure risk (e.g., stimulants), benzodiazepines, and dopaminergic psychotropic medications in the past month
Mini-Mental State Examination (MMSE) score (cognitive state) \<24
Premorbid NAART IQ estimate \<85
Visual disturbance: \<20/40 Snellen visual acuity
Left/mixed handedness (Annett criteria)
Binge drinking (as defined by NIAA criteria: consuming 5 or more drinks (male), or 4 or more drinks (female), in about 2 hours.) in the week before, and/or \>3 drinks/day for the 3 days before, and/or alcohol in the last 12 hrs before, any alcohol on tFUS scan day, confirmed at screening and scan days (to avoid tFUS during alcohol withdrawal). Alcohol/nicotine/caffeine/cannabis use (below SCID-5 SUD and binge levels) will be allowed
Unable to understand English
Any implanted neural device since it is not known whether tFUS would interfere with other implanted neural devices
Color blind
Clareo Health | Examination of Transcranial Focused Ultrasound on Brain Activity in Adults With Cocaine Use Disorder
