Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Assiut University
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult patients aged \> 18 years.
Confirmed diagnosis of metabolic dysfunction-associated steatotic liver disease (MASLD), defined as hepatic steatosis on abdominal ultrasound in the presence of at least one cardiometabolic risk factor (e.g., overweight/obesity, type 2 diabetes, or hypertension).
Newly diagnosed or pre-existing overt or subclinical hypothyroidism (for cases) or documented euthyroid status (for controls).
Availability of complete clinical and laboratory data required to calculate non-invasive liver fibrosis scores (FIB-4 index and NAFLD Fibrosis Score).
Provision of written informed consent to participate in the study.
You may not be if
Hyperthyroidism, history of thyroidectomy, or prior radioactive iodine therapy.
Chronic viral hepatitis (hepatitis B virus or hepatitis C virus).
Other secondary or specific chronic liver diseases (autoimmune hepatitis, primary biliary cholangitis, Wilson's disease, or hemochromatosis).
Decompensated liver cirrhosis or established hepatocellular carcinoma (HCC).
