Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry
CONTACT
Lead
Hoffmann-La Roche
Age
50–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Evidence of AD pathological process, as confirmed by either amyloid positron emission tomography (PET) scan or cerebrospinal fluid (CSF)
Mild cognitive impairment (MCI) or mild dementia due to AD
Able to swallow whole capsules
Body mass index (BMI) within the range of 18-34 kilograms per square metre (kg/m²) (at screening)
Availability of an appropriate study partner
You may not be if
Any evidence of a condition other than AD that may affect cognition
Participants must not have unstable or clinically significant cardiovascular disease within the last year, chronic uncontrolled hypertension, or clinically significant electrocardiogram (ECG) abnormalities
History or presence of clinically significant cerebrovascular disease
Clinically significant cerebral abnormalities on magnetic resonance imaging (MRI)
