Clareo Health | Effectiveness of Greater Occipital Nerve and Supratrochlear Nerve Pulsed Radiofrequency Versus Botulinum Toxin Type A Injection in Chronic Migraine
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Assiut University
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
• Age between 18 and 65 years, either sex.
* Diagnosis of chronic migraine according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria (headache occurring on ≥15 days/month for \>3 months, with migrainous features on ≥8 days/month).
* Inadequate response, intolerance, or contraindication to at least one standard oral preventive medication (e.g., amitriptyline, propranolol, topiramate, flunarizine, valproate).
* Stable dose of any concurrent prophylactic medication for at least 4 weeks prior to enrolment, with no planned change during the study period.
* Willingness and ability to complete headache diaries and follow-up visits.
You may not be if
• Other primary headache disorders (tension-type headache, cluster headache, hemicrania continua) as the predominant headache type.
* Secondary headache due to an identifiable structural, infectious, vascular, or neoplastic cause (confirmed or suspected by history/imaging).
* Prior botulinum toxin injection or radiofrequency procedure for headache within the last 6 months.
* Known hypersensitivity or allergy to botulinum toxin or to local anesthetics.
