3. Not currently receiving dialysis at time of screening.
4. Hemoglobin at presentation: 8.0-10 g/dL, serum ferritin \> 100 ng/mL at screening and transferrin saturation (TSAT) \> 20% at screening.
You may not be if
1. Clinically significant gastrointestinal bleeding, major surgery or RBCs transfusion in last 4 weeks
2. Pregnant, breast-feeding, not agreed to use contraception
3. Uncontrolled hypertension (\>180/100 mmHg).
4. Recent major cardiovascular event including acute coronary syndrome or stroke, or in the past 3 months, chronic liver disease (ALT OR AST \> 40 IU, hepatitis B or C)
5. Use of any experimental/investigational drug within 30 days of screening or know hypersensitivity against trial drugs
6. Active or high risk malignancy or treatment for malignancy with in the past 2 years.
7. Uncorrected iron deficiency despite iron supplementations.
8. Acute sepsis as evident by increase C-reactive protein (CRP), Total leukocyte count (TLC).
Clareo Health | Effect of Daprodustat and Epoetin Alpha on Anemia in Patients Not Undergoing Dialysis
