Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Age
18–70
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
1. Female, age 18 to 70 ;
2. Histopathologically confirmed previously untreated primary early-stage breast cancer, excluding occult breast cancer, inflammatory breast cancer, and Paget's disease of the breast;
3. Histopathologically confirmed primary early-stage breast cancer with no evidence of distant metastasis;
4. At least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1;
5. Eastern Cooperative Oncology Group (ECOG) performance status score ≤ 2;
6. Left ventricular ejection fraction (LVEF) ≥ 55%;
7. Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) ≤ 2× upper limit of normal (ULN); alkaline phosphatase ≤ 2× ULN; total bilirubin ≤ 2× ULN; serum creatinine ≤ 1.5× ULN;