The University of Texas Health Science Center, Houston
With
National Institutes of Health (NIH)
Age
9–19
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Family history of SSD (defined as first-degree (e.g., a parent or a sibling), second-degree (e.g., an uncle or a grandparent), or other combinations of biological relatives in the family have or likely have a diagnosis of SSD or other closely related severe mental illnesses equivalent to at least 25% of genetic sharing) per medical record review and/or parent/legal guardian report and confirmed by a structured interview
screening positive for two or more risk factors targeted by the intervention
Participants and parent(s)/legal guardian(s) agree to participate
psychiatrically stable and have no major changes in antidepressant, stimulant, or antipsychotic medication in the past 4 weeks.
You may not be if
Current or past history of psychotic disorders or clinical high risk for psychosis (CHR-p) per study interview
Current or past antipsychotic medication use to specifically treat a psychotic disorder
major medical and neurological conditions
moderate to severe intellectual disabilities or mild intellectual disabilities but expected to have difficulty completing the study assessments;
current drug or alcohol use that impacts functioning and study engagement;
Not able to give assent, permission, or consent.
Not able to undergo MRI.
Clareo Health | Developing Biomarker-Supported Schizophrenia Spectrum Disorder (SSD) Prevention