Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Patient with major neurocognitive disorder diagnosed (dementia syndrome)
Pregnant, laboring, or breastfeeding female patients
Patient deprived of liberty by judicial or administrative decision. Patient in psychiatric care under constraints may be included.
For patients accepting the lumbar punction: patients who are unable to control themselves and are likely to engage in physical or violent behavior.

Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment