Attendance at a participating GP practice in Canton Zurich or adjacent canton (maximum 1 hour travel time), or self-presentation via study microsite
At least one trigger criterion fulfilled: metabolic trigger (new-onset type 2 diabetes mellitus diagnosed within 24 months AND unintentional weight loss \>5% body weight within 3 months) OR familial/genetic trigger (≥2 first-degree relatives with PDAC, or ≥1 first-degree relative with PDAC, or BRCA1/2 germline mutation, or CDKN2A mutation); combined with age ≥60 years
Written informed consent
Sufficient German or English language skills for study communication
You may not be if
Prior or current diagnosis of pancreatic carcinoma or pre-malignant pancreatic lesion
Contraindication to MRI (metallic implants, severe claustrophobia without available alternative)
Active untreated psychiatric condition impairing capacity to consent
Pregnancy
Incapacity to provide informed consent
Clareo Health | Structured Case-Finding for Pancreatic Ductal Adenocarcinoma in Swiss Primary Care: A Feasibility Study