The investigators aim to evaluate how inflammation changes in individuals with lupus and to identify molecules and gut bacteria that may help predict disease flares. Blood and stool samples will be analyzed in the laboratory and compared with samples collected from the same participants following dietary changes.
This is an exploratory study designed to generate preliminary data on the short-term effects of dietary changes and treatment on blood biomarkers and the gut microbiome. The findings may provide insights into the mechanisms underlying lupus and could ultimately contribute to the development of new therapeutic approaches.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients who meet the 2019 EULAR/ACR Classification Criteria for SLE
patients who are on Cellcept or Myfortic for at least 3 months prior to screening
patients with a score of ≥55 on the Patient Reported Outcomes Measurement Information System (PROMIS) Pain interference scale.
You may not be if
pregnant or lactating patients,
patients with food allergy
patients on antibiotics within 4 weeks of the screening
patients that change the SLE therapy during the length of the study (12 weeks).
Clareo Health | Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous
