Maintaining Intraoperative Mean Arterial Pressure at 85 mmHg or Higher to Reduce Postoperative Delirium in Older Patients With Arterial Hypertension Having Non-cardiac Surgery
Germany's Federal Ministry of Research, Technology and Space (BMFTR)
Age
65–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
To be eligible for trial inclusion, patients must:
1\) be able to provide informed consent, AND
2\) be ≥65 years old, AND
3\) be scheduled for elective non-cardiac surgery with general anesthesia that is expected to last ≥120 minutes, AND
4\) have chronic arterial hypertension requiring antihypertensive medication OR have a systolic arterial pressure ≥140 mmHg or diastolic arterial pressure ≥90 mmHg on a measurement performed within the previous year, AND
5\) be at high risk for postoperative delirium because: American Society of Anesthesiologists physical status class III or IV OR Charlson Comorbidity Index ≥3 points (please see Appendix 1) OR frailty (documented in medical records or clinical diagnosis)
You may not be if
solid organ transplant surgery
intracranial surgery
surgery in sitting position
sepsis
surgery in the previous 30 days
previous participation in ASPIRE-85
Clareo Health | Maintaining Intraoperative Mean Arterial Pressure at 85 mmHg or Higher to Reduce Postoperative Delirium in Older Patients With Arterial Hypertension Having Non-cardiac Surgery
