Assessment of [18F]-Fluorocellobiose ([18F]FCB) Pharmacokinetics in Healthy Volunteers and Subjects With Invasive Mold Infections

Study Description: This study is intended to assess the pharmacokinetics (distribution, metabolism and excretion) of the novel PET radiopharmaceutical \[18F\]FCB in healthy individuals and to evaluate whether radioactive signal accumulation will be seen in individuals with certain fungal infection after \[18F\]FCB injection Objectives: Primary: -To evaluate uptake of \[18F\]FCB in subjects with invasive fungal infections Secondary: * To study the pharmacokinetics and radiation dosimetry of \[18F\]FCB in healthy volunteers * To establish the safety of \[18F\]FCB in healthy volunteers and in subjects with mold infections Endpoints: Primary: -Standardized uptake values (SUV) values from the site of suspected fungal infection after injection of \[18F\]FCB Secondary: -SUV values from various organs after injection of \[18F\]FCB, Organ time-activity curves (from dynamic data 1-60 minutes after injection), Radiation dose to organs of the body, Safety evaluation tests