Finding studies
Finding studies
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Brandon G. Smaglo, MD
CONTACT
Lead
M.D. Anderson Cancer Center
Primary Objective: To determine the safety and tolerability of the OnVagus device in patients wearing it while receiving chemotherapy. Secondary Objective: To determine the rate of cachexia arrest, as defined by weight stabilization or gain Exploratory Objectives: To analyze the changes in chemokine (C-C motif) ligand 2 (CCL2), tumor necrosis factor α (TNFa), acetylcholine (ACh), Growth/differentiation factor 15 (GDF15), Lipocalin-2 (LCN2), and liver function tests (LFTs) while patients receive vagal blockade. To determine the device's impact on progression-free survival (PFS) and overall survival (OS) between patients receiving vagal blockade.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted