Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Universidad de Almeria
Age
18–55
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18-55 years at the time of enrollment
Clinical diagnosis of Relapsing Multiple Sclerosis (RMS) or Progressive Multiple Sclerosis (PMS), with or without active progression, established per the 2014 McDonald diagnostic criteria
Expanded Disability Status Scale (EDSS) score of 0-3 at the time of screening
Time since initial MS diagnosis of at least 6 months
Active fatigue symptoms reported by the participant for at least the 6 months prior to enrollment
You may not be if
History of neuropsychiatric illness (including major depression, bipolar disorder, schizophrenia, or any anxiety disorder) prior to the onset of multiple sclerosis
Diagnosis of neuromyelitis optica spectrum disorder (Devic's disease)
Presence of any other central nervous system disease
Disease duration greater than 10 years combined with an EDSS score of ≤ 2
Visual impairment secondary to optic neuritis, internuclear ophthalmoplegia (oculomotor disorder), or any other uncorrected visual impairment that would affect task performance on cognitive assessments
Current pharmacological treatment for fatigue or depression
Current neuropsychiatric pharmacological treatment, including any antidepressant, anxiolytic, neuroleptic, or anticonvulsant medication
Clinical relapse requiring corticosteroid treatment in the 3 months prior to enrollment
Severe upper-limb motor deficit that would prevent task performance on neuropsychological assessments
