Age

18–79

Sex

ALL

Healthy volunteers

Not accepted

Signed informed consent
BMI ≥30 kg/m2 (obese) or BMI ≥27 kg/m2 (overweight) and presence of ≥1 of the obesity related comorbidities.

Previously documented diagnosis of type 1 diabetes, type 2 diabetes, or any other type of diabetes.
Self-reported change in body weight \>5 kg within 3 months before Screening.
Have prior or planned surgical or non-surgical treatment for obesity.
Have or plan to have endoscopic and/or device-based therapy for obesity.
Have obesity induced by other endocrine disorders.
Impaired renal function at Screening
Chronic malabsorption

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)