Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Participant is willing and able to give informed consent for participation in the study.
Adult patients (age \>/= 18y)
Diagnosis of MS
Confirmed program of autologous HSCT according to standard EBMT indications (any conditioning regimen considered standard, BEAM or Cyclophosphamide)
ATLG (total dose 30 mg/kg over 3 days: 10 mg/kg on days -3, -2 and -1) in the conditioning regimen.

Subjects that did not accept to sign the informed consent.
Use of ATG.
Contraindications to HSCT procedures (including pregnancy and breast feeding, uncontrolled active infections)

ATLG Levels in Autologous HSCT for Multiple Sclerosis