Impact of NOL - Nociception Level Index Intraoperative Monitoring on Perioperative Outcomes in Spine Surgery - a Quality Improvement Pilot

The study will assess the impact of intraoperative use of NOL nociception monitoring in in-hospital spine surgery procedures performed under general anesthesia on post operative patient outcomes. The study is designed as a quality improvement project with the prospective outcomes to be compared to a retrospective matched cohort. The objective of this study is to evaluate the clinical impact of the device on intraoperative and post operative patient outcomes and institutional metrics when used to guide intraoperative analgesia dosing in patients undergoing spine surgery under general anesthesia when compared to a case controlled retrospective cohort. The clinical impact will also be translated into economic metrics. Secondary endpoints 1. Reduction in time to extubation 2. Reduction in time to PACU discharge readiness 3. Reduction in anesthesia related adverse events: 1. PONV 2. Respiratory depression defined as respiratory rate (RR) below 8 respirations per minute (RPM) for 1 minute. Saturation of less than 90% for 1 minute under continuous monitoring 3. Somnolence 4. Sedation (Pasero score) 5. Discharge readiness (modified Aldrete score) 6. PACU pain intensity (NRS pain intensity ratings measured according to SOC) 6.3 Exploratory endpoints INTRAOPERATIVE 1. Reduction in hemodynamic instability (hypertension, hypotensive events) 2. Use of vasoactive medication (ephedrine, phenylephrine, norepinephrine, atropine) 3. Association between time spent with NOL values above 25 and PACU pain intensity ratings WARD - up to 48 hours post surgery 1. Patient reported satisfaction levels using questionnaire QR15 2. Pain intensity (Time points: NRS according to the SOC)) 3. 48 hours post-operative opioid consumption 4. Requirement for Acute Pain Service consultation 5. Reduction in rescue opioid requirements 6. Ketamine prescription on the ward 7. Opioid prescription on the ward 8. PONV medication consumption 9. Clinician survey on the device