1. Must have reached the age of majority in the jurisdiction where enrolled (18 years; Alabama/Nebraska 19; Puerto Rico 21).
2. Must have histologically proven GI cancer seen at the site within the 20 years preceding activation, and are:
1. Deceased, or
2. Lost to follow-up ( \>1 year lapse in contact since last visit).
Prospective Cohort:
1. Must have reached the age of majority in the jurisdiction where enrolled (18 years; Alabama/Nebraska 19; Puerto Rico 21).
2. Must have histologically proven Gastrointestinal (GI) cancer.
3. Patient or legally authorized representative capable of understanding and willing to provide signed informed consent (assent if applicable).
4. Patient/Legally Authorized Representative (LAR) agrees to collection of clinical data and information available on archival tissue and subsequent excess specimens obtained as part of standard-of-care.
You may not be if
Retrospective Cohort:
1\. Cases in which patient's medical chart denotes restricted use of health information.
Prospective Cohort:
1\. Prisoners will not be approached for participation.
Clareo Health | The Canopy Cancer Collective Clinical Registry Protocol
