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RECRUITINGPhase 1/2NCT07587515

Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

This Phase 1b/2a study will primarily investigate the safety and tolerability of EYC-0305 delivered by intravitreal (IVT) injection every 24 weeks in patients with neovascular (wet) age-related macula...

Lead sponsor: Eyconis INC.•5 U.S. locations•View source on ClinicalTrials.gov

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Contacts

Kim Reed, OD, FAAO

CONTACT

1-866-392-6647 info@eyconis.com

Karen Chu, MS

CONTACT

1-866-392-6647 info@eyconis.com

Sponsors

Lead Sponsor

Eyconis INC.

Age

50 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Men or women 50 years and older with neovascular (wet) AMD meeting all study-specified eligibility criteria
•Willing and able to comply with clinic visits and study-related procedures
•Provide signed informed consent

Exclusion Criteria

•Known hypersensitivity or known allergy that would preclude study drug administration
•Inability to obtain ophthalmic imaging, eg, due to media opacity, inadequate pupillary dilation, allergy to fluorescein dye or lack of venous access
•Uncontrolled diabetes mellitus
•History of cerebrovascular accident (CVA) or myocardial infarction within 180 days of the Day 1 visit
•Renal failure, dialysis, or history of renal transplant
•Concurrent psychiatric or medical condition that in the opinion of the Investigator will interfere with study participation or completion
•Pregnant or breastfeeding women

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 22, 2026Terms

Trial snapshot

StatusRECRUITING

PhasePHASE1/PHASE2

Enrollment30

Start dateMay 2026

Last updatedMay 22, 2026

Condition

Neovascular (Wet) Age-Related Macular Degeneration

Locations shown

Beverly Hills, CA

Beverly Hills, California

Erie, PA

Erie, Pennsylvania

Bellaire, TX

Bellaire, Texas

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 22, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions