Histidine Supplementation for Antitumor Immunity in Colorectal Cancer

Exclusion Criteria

• •1. Participation in other interventional clinical trials (including drugs, nutritional supplements, medical devices, etc.) within 4 weeks prior to enrollment.
• •2. Presence of ascites, severe diarrhea, intractable vomiting, severe malabsorption syndrome, paralysis, mechanical intestinal obstruction, or active gastrointestinal bleeding.
• •3. Allergy to sample components.
• •4. Current use of other nutritional supplements that may affect the validity and effectiveness of the study results.
• •5. Pregnant, lactating female patients or women with fertility who test positive in the baseline pregnancy test.
• •6. Presence of cognitive impairments or mental illnesses that prevent understanding of the study procedures.
• •7. Presence of any other conditions, judged by the researcher, make the participant unsuitable for participation in the study.