Biopsy-confirmed localized prostate cancer (Grade Group ≥ 2). Salvage cryoablation cases may be included.
Unifocal disease visible on multiparametric MRI (mpMRI) and amenable to focal or whole gland cryoablation.
Prostate-specific antigen (PSA) \< 20 ng/ml.
No metastatic disease on Prostate-Specific Membrane Antigen (PSMA) PET/CT, when recommended per National Comprehensive Cancer Network (NCCN) guidelines.
Eligible for and consenting to transperineal cryoablation under anesthesia.
Willingness to comply with post-procedure follow-up, including PSA testing and imaging.
Cryoablation which requires treatment of the posterior prostate as per clinician judgement.
You may not be if
Evidence of metastatic disease.
Prior radiation therapy to the area of the prostate.
Active rectal or urinary tract infection.
Known allergy to hyaluronic acid products or contrast agents.
Inability to tolerate MRI.
Inability or unwillingness to comply with study follow-up.
Clareo Health | Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)
