Physical Activity Directly Before Immunotherapy (Nivolumab and Ipilimumab) in Melanoma

Exclusion Criteria

• •Major surgery within 2 weeks prior to the start of the study intervention, or participants who have not fully recovered from the effects of a previous surgery.
• •Participants with a diagnosed immunodeficiency, or those receiving chronic systemic corticosteroid therapy (at a dose greater than 10 mg prednisone equivalent per day), or any other form of immunosuppressive therapy within 7 days prior to the first dose of the study medication.
• •Participants with an active infection requiring systemic therapy.
• •Participants with a known history of infection with human immunodeficiency virus (HIV) or hepatitis.