Long COVID is a multi-organ condition with persistent or delayed symptoms lasting weeks after infection, affecting physical and psychological function and reducing quality of life. It can occur regardless of age or initial disease severity, with prevalence ranging from 30% to 87.4%. Common symptoms include fatigue, cardiopulmonary issues, and neurological problems, collectively impairing daily functioning and mental health.
Exercise-based rehabilitation, including tele-exercise training, has emerged as a practical management strategy and may improve symptoms, cardiorespiratory fitness, and quality of life. However, current evidence remains limited due to small sample sizes and inconsistent protocols. Therefore, this study evaluated the effects of a 12-week tele-exercise program on symptoms, fitness, and quality of life in Taiwanese patients with long COVID compared with usual care.