Sebum Metabolomics and Lipidomics for Clinical Applications

Exclusion Criteria

• •Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
• •Presence of acute or chronic skin diseases, or chronic systemic diseases.
• •Use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
• •Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
• •Any other conditions deemed unsuitable for participation by the principal investigator.
• •B. Participants with Skin Diseases or Specific Skin Conditions
• •Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
• •Severe disease that may compromise skin integrity or pose a risk to participant safety.
• •Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
• •Any other conditions deemed unsuitable for participation by the principal investigator.
• •C. Participants Receiving Dermatological Treatments or Using Skincare Products
• •Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
• •Severe disease that may compromise skin integrity or pose a risk to participant safety.
• •Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
• •Any other conditions deemed unsuitable for participation by the principal investigator.
• •D. Healthy Participants Undergoing Short-term Antibiotic Intervention
• •Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
• •Known allergy or adverse reactions to the study intervention drug (topical antibiotic ointment containing bacitracin, polymyxin B, and neomycin).
• •Presence of visible skin disease, wounds, infection, inflammation, or other abnormal skin conditions at the sampling site.
• •Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
• •Any other conditions deemed unsuitable for participation by the principal investigator.